Neurolysis is a non-surgical procedure used to treat painful neuromas. Neuromas are benign growths of nerve tissue, or nerve tumors, that form when the nerves are irritated by surrounding tissue rubbing against them. Improper footwear that creates pressure on the foot, as well as foot structure abnormalities and injury to the nerves can cause or worsen neuromas. Symptoms of a neuroma include intense pain, swelling, tingling, numbness, and/ or a burning sensation in the toes and forefoot area. The pain usually intensifies when walking.

Neurolysis provides pain relief by interrupting nerve signals in the neuroma. A chemical such as ethanol mixed with a local anesthetic is injected into the nerve to temporarily destroy its fibers, providing pain relief.